Macrophages Dendritic cells B cells Properties of Professional Antigen- Presenting +++Phagocylosis by Antigen-specific Cells Antigen Phagocytosis uptake tissue dendritic cels. reoeptor (lg) +++ ++Viral infection ++++ MHC Inducble by bacteria and cytokines Constitutive Constitutive. expression Increases on activation -b+++ +++ +++0++++ Co-stimulator Constitutive;by mature Inducble Inducble delivery 一o+++ np089828oo -0++ ++十+ Antigen Particulate antigens. Peptides Soluble antigens. presented Intracellular and Viral antigens Toxins. extraoellular pathogens (allergens?) Viruses Lymphold tissue Lymphoid tissue. Location Connective tissue Connedtive tissue Lymphoid tissue. Body cavities Epithelia Peripheral blood @1997 Current Biology Ltd./Garland Publishing,Inc.Properties of Professional Antigen￾Presenting Cells