How do viruses contribute to Cancer? y Integrations that cause activation or inactivation of oncogenes or tumor suppressors(e.g RNA Viruses) y Expression of genes that alter key signal transduction pathways-this is our focus Chronic activation of inflammatory responses7  Integrations that cause activation or inactivation of oncogenes or tumor suppressors (e.g. RNA viruses)  Expression of genes that alter key signal transduction pathways - this is our focus  Chronic activation of inflammatory responses How do Viruses Contribute to Cancer?