definition The state in which Extreme Thirst/ Bluish Lips profound and Sale t Dry mouth widespread reduction of Rapid shallow Breathing effective tissure Chest perfusion leads first to eversible, if prolonged Cool 2E 2。 to irreversible cellular Clammy Pale skis下 Injury Skindefinition The state in which profound and widespread reduction of effective tissure perfusion leads first to reversible, if prolonged, to irreversible cellular injury