Antibodies →-4--4--1---1---4--4-- Antigen binding sites 几 Gene rearrangement Rearranged DNA Fab CL CL/ Fab Transcription RNA c F Heavy chain of an immunoglobulin Antibody molecule antibody productionAntibodies Antigen binding sites VH VL CH CH VL CL CH VH CH CL Fc Fab Fab Antibody Molecule ... ... ... V V D D J J C Gene rearrangement Rearranged DNA V D J C Transcription RNA V D J C Splicing mRNA V D J C Translation Heavy chain of an immunoglobulin Antibody Production