(A)The two general types of transcriptional regulation. In negative regulation, a repressor binds OFF to an operator and turns the operon off. In positive regulation,an activator protein binds upstream of the promoter and turns the operon on B)Graph showing the usual locations of activator sites relative to operators. Activator sites are usually farther upstream Each datum point Act valor sites indicates the middle of the known vo2a region on the dna where a regulatory protein binds LI 80-60-40-20 Base pairs coordinate(A) The two general types of transcriptional regulation. In negative regulation, a repressor binds to an operator and turns the operon off. In positive regulation, an activator protein binds upstream of the promoter and turns the operon on. (B) Graph showing the usual locations of activator sites relative to operators. Activator sites are usually farther upstream. Each datum point indicates the middle of the known region on the DNA where a regulatory protein binds