Concept of Hepatic insufficiency Severe damage in liver cells result in degeneration, necrosis, fibrosis and cirrhosis, manifesting as jaundice, bleeding, infection, renal dysfunction or encephalopathy, termed all together the syndrome of Hepatic insufficiency❖ Concept of Hepatic insufficiency Severe damage in liver cells result in degeneration, necrosis, fibrosis and cirrhosis, manifesting as jaundice, bleeding, infection, renal dysfunction or encephalopathy, termed all together the syndrome of Hepatic insufficiency 8