the bad and drowsy feelings were significantly to sweet almond oil and lavender.There was no decreased (p-value <0.05). significant asymmetry(p-value >0.05)as Fig.1.The topographic map shows obviously more scattering EEG data power in alpha brain,particularly in bilateral temporal The EEG power was calculated for each and central area after smelling lavender compared frequency band among resting,sweet almond oil, with resting and sweet almond oil as shown in Fig.2. and lavender oil inhalation.The studied areas were divided into the left anterior(Fpl,F3,F7),right anterior The analysis of male and female groups (Fp2,F4,F8),right posterior(P4,T6,02),left posterior Mean different score of autonomic nervous (P3,T5,O1),and middle(Fcz,Cz,Cpz)20)shown each system,mood state and power of brain during lavender band power with theta,alphal,alpha2,Beta(Table 4)oil inhalation when compare to sweet almond oil from and expressed by topographic maps in Fig.1.There 10 male and 10 female group demonstrated that there were noticeable changes of band power in theta and were no significant change observed between both alpha waves that significantly increased during the gender groups(p-value >0.05,data not shown). lavender inhalation in all brains areas(p-value <0.05) However,band powers in beta waves were not Discussion significantly different(p-value>0.05,data not shown). In the present research,lavender oil was The present study examined changes in the anterior, administered by inhalation to healthy subjects.Brain posterior alpha asymmetry(left and right side)response wave activity and ANS parameters (blood pressure, Table 4.Mean power values in eyes closed during sweet almond oil and lavender Area Eye close (n=20) S0(n=20) L0(n=20) p-value p-value mean mean mean eye close and SO SO and LO (t-test) (t-test) Theta power(uV凸 Left anterior 1.91 1.54 2.16 0.590 0.001* Right anterion 2.00 1.62 2.27 0.090 0.001* Center 2.68 2.10 3.05 0.030* 0.006* Left posterior 1.13 1.08 1.34 0.550 0.002* Right posterior 1.15 1.10 1.38 0.025* 0.025* Alphal power(uV2) Left anterior 3.44 3.71 6.94 0.218 0.001* Right anterior 4.02 4.38 7.70 0.218 0.001* Center 4.78 4.83 9.40 0.156 0.001* Left posterior 4.16 4.56 6.86 0.218 0.001* Right posterior 4.29 4.46 8.79 0.001* 0.001* Alpha2 power (uv2) Left anterior 1.51 1.43 2.09 0.911 0.011* Right anterion 1.63 1.50 2.23 0.575 0.006* Center 2.28 1.96 3.09 0.179 0.003* Left posterior 2.37 2.31 3.41 0.823 0.008* Right posterior 2.76 2.51 4.10 0.002* 0.002* Beta power(uV2) Left anterior 0.31 0.35 0.33 0.167 0.351 Right anterior 0.32 0.36 0.35 0.156 0.433 Center 0.36 0.41 0.41 0.086 0.627 Left posterior 0.31 0.37 0.36 0.156 0.852 Right posterior 0.31 0.36 0.37 0.794 0.794 Significant difference,p-value<0.05 SO=sweet almond oil;LO lavender oil 602 J MedAssoc Thai Vol 95 No.4 2012602 J Med Assoc Thai Vol. 95 No. 4 2012 the bad and drowsy feelings were significantly decreased (p-value <0.05). EEG data The EEG power was calculated for each frequency band among resting, sweet almond oil, and lavender oil inhalation. The studied areas were divided into the left anterior (Fp1, F3, F7), right anterior (Fp2, F4, F8), right posterior (P4, T6, O2), left posterior (P3, T5, O1), and middle (Fcz, Cz, Cpz) (20) shown each band power with theta, alpha1, alpha2, Beta (Table 4) and expressed by topographic maps in Fig. 1. There were noticeable changes of band power in theta and alpha waves that significantly increased during the lavender inhalation in all brains areas (p-value <0.05). However, band powers in beta waves were not significantly different (p-value > 0.05, data not shown). The present study examined changes in the anterior, posterior alpha asymmetry (left and right side) response to sweet almond oil and lavender. There was no significant asymmetry (p-value > 0.05) as Fig. 1. The topographic map shows obviously more scattering power in alpha brain, particularly in bilateral temporal and central area after smelling lavender compared with resting and sweet almond oil as shown in Fig. 2. The analysis of male and female groups Mean different score of autonomic nervous system, mood state and power of brain during lavender oil inhalation when compare to sweet almond oil from 10 male and 10 female group demonstrated that there were no significant change observed between both gender groups (p-value > 0.05, data not shown). Discussion In the present research, lavender oil was administered by inhalation to healthy subjects. Brain wave activity and ANS parameters (blood pressure, Area Eye close (n = 20) SO (n = 20) LO (n = 20) p-value p-value mean mean mean eye close and SO SO and LO (t-test) (t-test) Theta power (μV2 ) Left anterior 1.91 1.54 2.16 0.590 0.001* Right anterior 2.00 1.62 2.27 0.090 0.001* Center 2.68 2.10 3.05 0.030* 0.006* Left posterior 1.13 1.08 1.34 0.550 0.002* Right posterior 1.15 1.10 1.38 0.025* 0.025* Alpha1 power (μV2 ) Left anterior 3.44 3.71 6.94 0.218 0.001* Right anterior 4.02 4.38 7.70 0.218 0.001* Center 4.78 4.83 9.40 0.156 0.001* Left posterior 4.16 4.56 6.86 0.218 0.001* Right posterior 4.29 4.46 8.79 0.001* 0.001* Alpha2 power (μV2 ) Left anterior 1.51 1.43 2.09 0.911 0.011* Right anterior 1.63 1.50 2.23 0.575 0.006* Center 2.28 1.96 3.09 0.179 0.003* Left posterior 2.37 2.31 3.41 0.823 0.008* Right posterior 2.76 2.51 4.10 0.002* 0.002* Beta power (μV2 ) Left anterior 0.31 0.35 0.33 0.167 0.351 Right anterior 0.32 0.36 0.35 0.156 0.433 Center 0.36 0.41 0.41 0.086 0.627 Left posterior 0.31 0.37 0.36 0.156 0.852 Right posterior 0.31 0.36 0.37 0.794 0.794 * Significant difference, p-value < 0.05 SO = sweet almond oil; LO = lavender oil Table 4. Mean power values in eyes closed during sweet almond oil and lavender