消除反应的定向 Orientation) C-C-R E1反应: °B H CH3CH--CH(CH3)2 CH3 CH-CH(CH3)2 CH3CH=C(CH3)2 X 热力学控制产物 遵循 Sayzaff:则 EICB反应: NCH3)3OH RNCH3)3 遵循 CH3 CH,CH--CH3->CH3 CH, CH2 Hofmann △,CH3CH2CH=CH2 规则 95%消除反应的定向 (Orientation) C C C L Hβ Hβ ' R CH3CH CH(CH3 ) 2 X B CH3CH CH(CH3 ) 2 －H CH3CH C(CH3 ) 2 E1反应： 热力学控制产物 遵循Sayzaff规则 E1CB反应： CH3 CH2 CH CH3 N(CH3 ) 3OH CH3 CH2 CH CH2 N(CH3 ) 3 △ CH3 CH2 CH CH2 95% 遵循 Hofmann 规则