Shanghai Medical College of Fudan University Final Exam of Medical Genetics in 2010-2011(1) MBBS 口A Section A: Multiple-choice Questions(20%) 1. ABCD 2. ABd 3. ACD 4CD 5BC 6.ACDE 7.ABCD 8ADE 9ABCE 10.AB Section B Term explanation short-answer questions(30%) 1. X Chromosome inactivation X Chromosome heterochromatin is condensed chromatin that unfolds and becomes transcriptionally active during some portion of the cell cycle Barr boa小y 2. Chromosome translocations Chromosomal abnormalities which occur when chromosomes break and the fragments rejoin to other chromosomes 3. Birth defect Birth defects are defined as abnormalities of structure, function, or body metabolism that are present at birth 4. Explain the classification of genetic diseasesShanghai Medical College of Fudan University Final Exam of Medical Genetics in 2010-2011 (1) MBBS □ A Section A: Multiple-choice Questions (20%) 1. ABCD 2. ABD 3. ACD 4.CD 5.BC 6.ACDE 7.ABCD .8ADE 9.ABCE 10.AB Section B Term explanation& Short-answer questions(30%) 1. X Chromosome inactivation X Chromosome heterochromatin is condensed chromatin that unfolds and becomes transcriptionally active during some portion of the cell cycle (Barr body). 2. Chromosome translocations Chromosomal abnormalities which occur when chromosomes break and the fragments rejoin to other chromosomes. 3. Birth defect Birth defects are defined as abnormalities of structure, function, or body metabolism that are present at birth. 4. Explain the classification of genetic diseases