2. Dalziel SR, Lim VK, Lambert A, McCarthy D, Parag V, Rodgers ACKNOWLEDGEMENTS Aet al Antenatal exposure to betamethasone: psychological func- tioning and health related quality of life 31 years after inclusion P Crowley's first, unstructured review of antenatal corticosteroids a randomised controlled trial. BM] 2005: 331: 665-8 was conducted at the suggestion of Professor Dennis Hawkins 3. Table 45.12 In: Chalmers I, Enkin M, Keirse MINC, eds Effec- 1980. Dr Anne Anderson encouraged her to use it as a basis for an early meta-analysis in 1981. Her work at the National perina- tive care in pregnancy and childbirth. Oxford: Oxford University tal Epidemiology Unit in 1980 to 1981 was funded by the Na- ress1989:754. tional Maternity Hospital, Dublin at the suggestion of the then Authors reply Master, Dr Dermot MacDonald. This review was first published Since Effective Care in Pregnancy and Childbirth appeared, nine in structured form on the Oxford Database of Perinatal Trials in randomised controlled trials of antenatal corticosteroids have been 1989. The preparation and continued updating of the original published. These trials are now included in the updated Cochrane iew would have been impossible without the help of lain and review. This updated review shows the contribution of each study Jan Chalmers, Marc Keirse, Jini Hetherington, Sonja Henderson to the outcome measures, and describes the methodological quality and Professor Zarko Alfirevic of each included trial Acknowledgements to Professor James Neilson and Professor Jane For Liggins 1972a, the previous Cochrane review(Crowley 1996) Harding for their help with the current update. Many thanks to included data that were published at that time Hence, data for Sonja Henderson for sound advice at all times. Acknowledger perinatal death(stillbirth or death in the first week of life)were also to all the authors who provided us with additional data. led owever, the updated Cochrane review includes an in- ins 1972a. As Part of the tention-to-treat analysis of the original data from Lx, (Crowley been commented on by three peers(an editor and two referees These data were not available for the previous re 1996).This updated review therefore now includes data for neona. who are external to the editorial team), one or more members tal death( death in the first 28 days of life) in Liggins 1972a of the Pregnancy and Childbirth Group's international panel of consumers and the Group's Statistical Adviser. Data reported for Schmidt 1984 included a third arm of women and infants who had been excluded from randomisation this dy is now excluded from the review SOURCES OF SUPPORT (Suumary of response from Devender Roberts and Stuart Dalziel ay2006, External sources of support David Huichon The University of Liverpool UK Liverpool Womens NHS Foundation Trust UK POTENTIAL CONFLICT OF University of Auckland NEW ZEALAND INTEREST Internal sources of support No sources of support supplied Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth(rev Copyright @2006 The Cochrane Collaboration. Published by John wiley& Sons, Ltd 第110页2. Dalziel SR, Lim VK, Lambert A, McCarthy D, ParagV,Rodgers A et al. Antenatal exposure to betamethasone: psychological functioning and health related quality of life 31 years after inclusion in a randomised controlled trial. BMJ 2005;331:665-8. 3. Table 45.12 In: ChalmersI, Enkin M, KeirseMJNC,eds. Effective care in pregnancy and childbirth. Oxford: Oxford University Press, 1989:754. Author’s reply Since Effective Care in Pregnancy and Childbirth appeared, nine randomised controlled trials ofantenatalcorticosteroids have been published. Thesetrials are now included in the updated Cochrane review. This updated review shows the contribution of each study to the outcomemeasures,and describesthemethodological quality of each included trial. For Liggins 1972a, the previous Cochrane review (Crowley 1996) included data that were published at that time Hence, data for perinatal death (stillbirth or death in the first week of life) were included. However, the updated Cochrane review includes an intention-to-treat analysis of the original data from Liggins 1972a. These data were not available for the previous review (Crowley 1996).This updated reviewtherefore nowincludes datafor neonatal death (death in the first 28 days of life) in Liggins 1972a. Data reported for Schmidt 1984 included a third arm of women and infants who had been excluded from randomisation. This study is now excluded from the review. (Suumary of response from Devender Roberts and Stuart Dalziel, May 2006.) Contributors David Hutchon -- P O T E N T I A L C O N F L I C T O F I N T E R E S T None known. A C K N O W L E D G E M E N T S P Crowley’s first, unstructured review of antenatal corticosteroids was conducted at the suggestion of Professor Dennis Hawkins in 1980. Dr Anne Anderson encouraged her to use it as a basis for an early meta-analysis in 1981. Her work at the National Perinatal Epidemiology Unit in 1980 to 1981 was funded by the National Maternity Hospital, Dublin at the suggestion of the then Master, Dr Dermot MacDonald. This review was first published in structured form on the Oxford Database of Perinatal Trials in 1989. The preparation and continued updating of the original review would have been impossible without the help of Iain and Jan Chalmers, Marc Keirse, Jini Hetherington, Sonja Henderson and Professor Zarko Alfirevic. Acknowledgements to Professor James Neilson and Professor Jane Harding for their help with the current update. Many thanks to SonjaHenderson forsound adviceatall times. Acknowledgements also to all the authors who provided us with additional data. As part of the pre-publication editorial process, this review has been commented on by three peers (an editor and two referees who are external to the editorial team), one or more members of the Pregnancy and Childbirth Group’s international panel of consumers and the Group’s Statistical Adviser. S O U R C E S O F S U P P O R T External sources of support • Trinity College Dublin IRELAND • The University of Liverpool UK • Liverpool Women’s NHS Foundation Trust UK • University of Auckland NEW ZEALAND Internal sources of support • No sources of support supplied Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth (Review) 16 Copyright © 2006 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd 第 110 页