Antithyroid Drugs(ATD)抗甲状腺药物 Class Summary: ■Thiourea(疏脲类)：Propylthiouracil(PTU,丙硫氧嘧啶) ■Imidazoles(咪唑类)：carbimazole(卡比马唑，甲亢平)，thiamazole(甲巯咪唑，他巴唑) ■Mechanism: They principally inhibit the function of TPO,reducing iodide organification and coupling processes,thereby preventing synthesis of thyroid hormones. They also reduce thyroid antibody levels. .Inhibits deiodination(脱碘)ofT4toT3■ Class Summary： ■ Thiourea (硫脲类）：Propylthiouracil（ PTU，丙硫氧嘧啶） ■ Imidazoles（咪唑类）：carbimazole(卡比马唑,甲亢平）, thiamazole( 甲巯咪唑,他巴唑） ■ Mechanism： ■ They principally inhibit the function of TPO, reducing iodide organification and coupling processes, thereby preventing synthesis of thyroid hormones. ■ They also reduce thyroid antibody levels. ■ Inhibits deiodination（脱碘）of T4 to T3 Antithyroid Drugs（ATD）抗甲状腺药物