Defining Proteomics Branch of discovery science focusing on proteins a In 1994 defined as the complete set of proteins that is expressed and modified following expression by the entire genome in the lifetime of a cell. If we look at an organism it means that we are looking at the proteome of 3 trillion of cells and -1000 different cell types with different protein profiles a Can be more specific such as the complement of proteins expressed by a cell at any one time 1 Today proteomics is a scientific discipline that will bridge the gap between our understanding of genome sequences and cellular behavior 0/27/2005 Chaoqun Wu, Fudan University10/27/2005 Chaoqun Wu, Fudan University Chaoqun Wu, Fudan University 2 Defining Proteomics Defining Proteomics Branch of discovery science focusing on proteins Branch of discovery science focusing on proteins In 1994 defined as In 1994 defined as “the complete set of proteins that is the complete set of proteins that is expressed and modified following expression by the expressed and modified following expression by the entire genome in the lifetime of a cell entire genome in the lifetime of a cell”. If we look at an . If we look at an organism it means that we are looking at the proteome of organism it means that we are looking at the proteome of 3 trillion of cells and ~1000 different cell types with 3 trillion of cells and ~1000 different cell types with different protein profiles. different protein profiles. Can be more specific such as the complement of Can be more specific such as the complement of proteins expressed by a cell at any one time. proteins expressed by a cell at any one time. Today proteomics is a scientifi Today proteomics is a scientific discipline that will bridge c discipline that will bridge the gap between our understanding of genome the gap between our understanding of genome sequences and cellular behavior. sequences and cellular behavior