Genetie factors Androgen excess PPAR ligands Hyperseborrhoea Regul with pro-infiammatory lipids 痤疮发病机制 neuropeptides Epithelial hyperproliferation Inflammation P acnes ( ductus seboglandularis acroinfundibulum) Dietary lipids Y Smoki Other Zouboulis CC, Eady A, Philpott M, Goldsmith LA, Orfanos C, cunliffe Wc Rosenfield R what is the pathogenesis of acne? Exp Dermato|2005:14:143-152. 2021/2/21 122021/2/21 12 Zouboulis CC, Eady A, Philpott M, Goldsmith LA, Orfanos C, cunliffe WC Rosenfield R. What is the pathogenesis of acne? Exp Dermatol 2005: 14: 143–152. 痤 疮 发 病 机 制