Medical Genetics Treatment Lifelong iG given IM or IV in the lowest dose that prevents recurrent infection is essential. Prompt, adequate antibiotic administration with each infection is crucial continuous antibiotics are sometimes indicated. Despite these measures, many patients develop persistent sinusitis bronchitis, and bronchiectasis Susceptibility to malignancy is increasedMedical Genetics Treatment Lifelong IG given IM or IV in the lowest dose that prevents recurrent infection is essential. Prompt, adequate antibiotic administration with each infection is crucial; continuous antibiotics are sometimes indicated. Despite these measures, many patients develop persistent sinusitis, bronchitis, and bronchiectasis. Susceptibility to malignancy is increased