上游充更大睾 Host cell Cell membrane 2 00 Virus Ribosomes 6 and mRNA Chromosomes Host nucleus Sites of drug action 1.Attachment to host cell 3.Control of DNA,RNA,and/or 5.Assembly of virions 2.Uncoating of virus,and protein production 6.Release of virions entry of viral nucleic acid 4.Production of viral subunits into host cell nucleus (Modified from Brody TM,Larner J,Minneman KP:Human pharmacology:molecular to clinical,ed 3,St Louis,1998 Mosby) Fig.39-1.Virus replication.Some viruses integrate into host chromosome with development of latency.Shanghai Jiao Tong University