Nuclear Magnetic Resonance-Bushberg Chapter 14 Diagnostic Radiology Imaging Physics Course Nuclear Magnetic Resonance-Chapter 14 othe nucleus and the roperties of matter How the NMR signal is generated and detected .T1 and T2 relaxation:how they arise and how they are Brent K.Stewart.PhD.DABMP ulse se Soft Tissue Transparency and First NMR Image edicine-MR an 参 ce (NM 3 9,19and26May2005Nuclear Magnetic Resonance – Bushberg Chapter 14 Diagnostic Radiology Imaging Physics Course 9, 19 and 26 May 2005 1 © UW and Brent K. Stewart, PhD, DABMP 1 Nuclear Magnetic Resonance Nuclear Magnetic Resonance – Chapter 14 Brent K. Stewart, PhD, DABMP Professor, Radiology and Medical Education Director, Diagnostic Physics a copy of this lecture may be found at: a copy of this lecture may be found at: http://courses.washington.edu/radxphys/ ington.edu/radxphys/PhysicsCourse04-05.html © UW and Brent K. Stewart, PhD, DABMP 2 Take Aways: Five Things You should be able : Five Things You should be able to Explain after to Explain after the NMR Lectures the NMR Lectures ™ The magnetic characteristics of the nucleus and the The magnetic characteristics of the nucleus and the magnetic properties of matter magnetic properties of matter ™ How the NMR signal is generated and detected ™ T1 and T2 relaxation: T1 and T2 relaxation: how they arise and how they are how they arise and how they are measured ™ Pulse sequence methods used and pulse sequence Pulse sequence methods used and pulse sequence timing (e.g., TR and TE) and inherent NMR parameters timing (e.g., TR and TE) and inherent NMR parameters (e.g., T1 and T2) give rise to tissue contrast (e.g., T1 and T2) give rise to tissue contrast ™ How a 1D gradient can be used to provide an echo and How a 1D gradient can be used to provide an echo and allow for quick imaging with shallow flip angle sequences © UW and Brent K. Stewart, PhD, DABMP 3 Soft Tissue Transparency and First NMR Image c.f. Mokovski, A. Medical Imaging Systems, p. 3. © UW and Brent K. Stewart, PhD, DABMP 4 2003 Nobel Prize for Medicine for Medicine - MRI ™ Laterbur and Mansfield Laterbur and Mansfield (2003, medicine): (2003, medicine): discoveries concerning discoveries concerning magnetic resonance magnetic resonance imaging (MRI) imaging (MRI) ™ Rabi (1944, physics): Rabi (1944, physics): nuclear magnetic nuclear magnetic resonance (NMR) resonance (NMR) methodology ™ Bloch and Purcell (1952, Bloch and Purcell (1952, physics): NMR precision physics): NMR precision measurements ™ Ernst (1991, chemistry): Ernst (1991, chemistry): high-resolution NMR resolution NMR spectroscopy