Additional Resources 277 277 Chapter 15 SOLID-STATE NMR SPECTROSCOPY 15.1 Why Study Materials in the Solid State? 283 15.2 Why is NMR of Solids Different from NMR of Fluids? 15.3 Chemical Shifts in Solids 15.4 Spin-Spin Coupling 15.5 Quadrupole Coupling 297 15.6 Overcoming Long T]: Cross Polarization Chapter Summary Additional Resources Review Problems Chapter 16 NMR IN MEDICINE AND BIOLOGY: NMR IMAGING 16.1 A window into Anatomy and Physiology 306 16.2 Biomedical NMR 16.3 Pictures with NMR: Magnetic Resonance Imaging 16.4 Image Contrast 16.5 Higher Dimensional Imaging 32 16.6 Chemical Shift Imaging 16.7 NMR Movies: Echo Planar Imaging 16.8 NMR Microscopy 16.9 In Vivo NMR Spectroscopy 326 16.10 Nonmedical Applications of MRI Chapter Summary Additional Resources 33 Appendix 1 ANSWERS TO REVIEW PROBLEMS 334 Appendix 2 PERIODIC TABLE SUBJECT INDEX 370 CHEMICAL COMPOUNDS INDEX 379