Conjugate Addition of amine H R- C=CH H2CTNR2 The mannich reaction an eno ole R an iminium ion -8c1+,m比 C-C-CHaNR2 a B-aminoketone The Micheal reaction a mannich base21 Conjugate Addition of Amine R' C O H 2 C CH 2 NR 2 R' C '' O H C CH 2 HNR'' 2 + a β-aminoketone a Mannich base H 2 C NR 2 R' C '' OH CH an enole R an iminium ion + The Mannich Reaction The Micheal Reaction