The pathophysiology underlying angina pectoris Contractile AV state OXYGEN OXYGEN Oxygen Difference DEMAND SUPPLY Heart Regional Rate Myocardial Distribution Wall ↑ ISCHEMIA Tension Coronary Blood Flow LV Ventricular Coronary Aortic Vascular Pressure Volume Pressure ResistanceThe pathophysiology underlying angina pectoris OXYGEN DEMAND OXYGEN SUPPLY Contractile state Heart Rate Wall Tension ISCHEMIA AV Oxygen Difference Regional Myocardial Distribution Coronary Blood Flow LV Pressure Ventricular Volume Coronary Vascular Resistance Aortic Pressure