Genetic carrier normal parent n the parent (t14q21q 21 A14 A 144 X u XiM v XH mete 21 normal carrier 21-trisomy 14-trisomy nose monosomy Pathogenesis of translocation in 21-trisomy Still birthGenetic carrier in the parent normal parent 21 14 21 14 21 14 21 14 21 14 21 14 14 21 14 21 Gamete (t14q21q) 21 14 normal 21 14 carrier 21 14 21-trisomy 21 14 21- monosomy 21 14 14-trisomy 21 14 14- monosomy Still birth Pathogenesis of translocation in 21-trisomy