Genetic considerations n Genetics is only a"major influence There are may schizophrenia patients that do not have a family history. 口 Twin studies Heritability risk at -80% Increased risk even when raised apart a Schizophrenic phenotype genetically influenced not genetically determined Gene variants are usually within normal limits Genetics is only a "major" influence ◼ There are may schizophrenia patients that do not have a family history.  Twin studies ◼ Heritability risk at ~80% ◼ Increased risk even when raised apart  Schizophrenic phenotype ◼ genetically influenced ◼ not genetically determined ◼ Gene variants are usually within normal limits