Neisseria meningitidis 公公 Gn diplococci Serotypes A, B, C,Y, and W135 cause most invasive di sease. Virulence depends on: C capsular polysaccharide 2. LPS(endotoxin) 3. Pili 4.IgA protease 5. ompS geneNeisseria meningitidis  - GN diplococci  - Serotypes A,B,C,Y, and W135 cause most invasive disease.  - Virulence depends on: 1. Capsular polysaccharide 2. LPS(endotoxin) 3. Pili 4. IgA protease 5. ompS gene