Risk Factors 1. Medical conditions a Diabetes mellitus, hypertension b. Overweight---obesity(excess estrogen as a result of peripheral conversion of adrenally derived androstenedione by aromatization in fat) C Late menopauseRisk Factors 1. Medical conditions a. Diabetes mellitus, hypertension. b. Overweight---obesity (excess estrogen as a result of peripheral conversion of adrenally derived androstenedione by aromatization in fat). c. Late menopause