National Pesticide Program CHALLENGES Science Increasingly Complex and Changing Large Number of Chemicals to Review with Many Possible Adverse Outcomes Finite Resources and Time Sufficient,Credible Information to Make a Decision, not an Overwhelming Amount of Information Public Expectations for Scientific Soundness, Transparency,and Timeliness National Pesticide Program Vision for a New Toxicology Testing and Assessment Paradigm ·Integrative ·Hypothesis-Driven ·Efficient3 5 National Pesticide Program CHALLENGES • Science Increasingly Complex and Changing • Large Number of Chemicals to Review with Many Possible Adverse Outcomes • Finite Resources and Time • Sufficient, Credible Information to Make a Decision, not an Overwhelming Amount of Information • Public Expectations for Scientific Soundness, Transparency, and Timeliness 6 • Integrative • Hypothesis-Driven • Efficient National Pesticide Program Vision for a New Toxicology Testing and Assessment Paradigm