b, stratum spinosum structure LM,=4-10 layers polygonal cell with large round nucleus spinous processes slight basophilic cytoplasm EM: -tonofibrils lamellated granules /100-300nm membrane-coated /contain phospholipid and steroid intercellular bridges- Desmosomeb. stratum spinosum ---structure: LM: -4-10 layers polygonal cell with large round nucleus -spinous processes -slight basophilic cytoplasm EM: -tonofibrils -lamellated granules: /100-300nm membrane-coated /contain phospholipid and steroid -intercellular bridges- Desmosome