clinical features chronic ☆ acute pallor aRa⊥gor、 jaundice yperpyrex1a、 splenomegaly sore waist cholelithiasis HEmoglobinuria cRaplastic crisis JAundice、 anaemiaclinical features ❖chronic pallor 、 jaundice 、 splenomegaly cholelithiasis aplastic crisis ❖acute algor、 hyperpyrexia、 sore waist hemoglobinuria jaundice、 anaemia