Loss of p53 function occurs in more than 50% of human cancers These cancer cells are genetically unstable because they are unable to do the following Stop the cell cycling to allow time for DNA repair Carry out efficient DNA repair ∪ ndergo apoptosisLoss of p53 function occurs in more than 50% of human cancers!! •These cancer cells are genetically unstable because they are unable to do the following: • Stop the cell cycling to allow time for DNA repair • Carry out efficient DNA repair • Undergo apoptosis