Rabies virus (Rhabdovirus Transmitted by animal bite Virus multiplies in skeletal muscles,then brain cells causing encephalitis Initial symptoms may include muscle spasms of the mouth and pharynx and hydrophobia Furious rabies:animals are restless then highly excitable Paralytic rabies:animals seem unaware of surroundings Preexposure prophylaxis:Infection of human diploid cells vaccine Postexposure treatment:Vaccine immune globulin • Transmitted by animal bite • Virus multiplies in skeletal muscles, then brain cells causing encephalitis • Initial symptoms may include muscle spasms of the mouth and pharynx and hydrophobia • Furious rabies: animals are restless then highly excitable • Paralytic rabies: animals seem unaware of surroundings • Preexposure prophylaxis: Infection of human diploid cells vaccine • Postexposure treatment: Vaccine + immune globulin Rabies virus (Rhabdovirus)