Clinical manifestations) 1.Age:<40 2. Onset: insidiously 3. Pathology: enthesis 4. Clinical manifestation low back pain and stiffness arthritis eye disease cardiovascular disease【Clinical manifestations】 1. Age: <40 2. Onset: insidiously 3. Pathology: enthesis 4. Clinical manifestation： low back pain and stiffness arthritis eye disease cardiovascular disease -------