Eight histone proteins function as subunits in a multi-protein complex called a nucleosome Portions of two subunits(Ha and HB)interact in the core of the nucleosome. The figure below shows the a- helices where these two proteins interact Trp 72 Ph Trp p HA HB Figure by MIT OCW c) Based on the amino acids labeled in the diagram, what interactions keeps Ha and HB together? Circle all that apply. 3 pts covalent drogen nyaropnoDIc IonIc an der waals d)If tryptophan 72 mutates to become an arginine residue, indicate how the interaction between HA and HB would change. 2 pts becomes stronger becomes weaker remains the same an not be determined e)Explain your answer in d)in twelve(12)words or less. 3 pts Positive charged does'nt interact with hydrophobic side chain f)Based on the information given, circle all levels of structure possessed by histones within a nucleosome 4 pts primary seconda tertiary quaternary quinternary 6Eight histone proteins function as subunits in a multi-protein complex called a nucleosome. Portions of two subunits (HA and HB) interact in the core of the nucleosome. The figure below shows the α− helices where these two proteins interact. Trp Trp Trp Trp Trp Trp Trp Trp 72 HA HB 72 HA Phe Ile Phe Ile Figure by MIT OCW. c) Based on the amino acids labeled in the diagram, what interactions keeps HA and HB together? Circle all that apply. 3 pts covalent hydrogen hydrophobic ionic van der Waals d) If tryptophan 72 mutates to become an arginine residue, indicate how the interaction between HA and HB would change. 2 pts. becomes stronger becomes weaker remains the same can not be determined e) Explain your answer in d) in twelve (12) words or less. 3 pts Positive charged does’nt interact with hydrophobic side chain. f) Based on the information given, circle all levels of structure possessed by histones within a nucleosome. 4 pts primary secondary tertiary quaternary quinternary 6