Homology Modeling on a Genomic Scale · Requires automation Can't choose templates or fine-tune the alignment by hand MODBASE and 3D-CRUNCH http://alto.compbio.ucsfedu/modbase-cgi/index.cgi http://www.expasy.ch/swissmod/sm_3dcrunch.htm Automatic assessment is critical how reliable is the model?Homology Modeling on a Genomic Scale • Requires automation – Can’t choose templates or fine-tune the alignment by hand! • MODBASE and 3D-CRUNCH http://alto.compbio.ucsf.edu/modbase-cgi/index.cgi http://www.expasy.ch/swissmod/SM_3DCrunch.html • Automatic assessment is critical - how reliable is the model?