21.1 Introduction 21.2 Response elements identify genes under common regulation 21.3 There are many types of DNA-binding domains 21. A zinc finger motif is a DNA-binding domain 21.5 Steroid receptors are transcription factors 21.6 Steroid receptors have zinc fingers 21.7 Binding to the response element is activated by ligand-binding 21. 8 Steroid receptors recognize response elements by a combinatorial code 21.9 Homeodomains bind related targets in dna 21.10 Helix-loop-helix proteins interact by combinatorial association 21 11 Leucine zippers are involved in dimer formation 21 12 Transcription initiation requires changes in chromatin structure 21 13 Chromatin remodeling is an active process 21 14 Activation of transcription requires changes in nucleosome organization at the promoter 21 15 Histone acetylation and deacetylation control chromatin activity 21 16 Polycomb and trithorax are antagonistic repressors and activators 21 17 An LCR may control a domain 21. 1 8 Insulators block enhancer actions 21 19 Insulators can vary in strength 21.20 A domain has several types of elements 21.2 1 Gene expression is associated with demethylation 22 CpG islands are regulatory targets 消当21.1 Introduction 21.2 Response elements identify genes under common regulation 21.3 There are many types of DNA-binding domains 21.4 A zinc finger motif is a DNA-binding domain 21.5 Steroid receptors are transcription factors 21.6 Steroid receptors have zinc fingers 21.7 Binding to the response element is activated by ligand-binding 21.8 Steroid receptors recognize response elements by a combinatorial code 21.9 Homeodomains bind related targets in DNA 21.10 Helix-loop-helix proteins interact by combinatorial association 21.11 Leucine zippers are involved in dimer formation 21.12 Transcription initiation requires changes in chromatin structure 21.13 Chromatin remodeling is an active process 21.14 Activation of transcription requires changes in nucleosome organization at the promoter 21.15 Histone acetylation and deacetylation control chromatin activity 21.16 Polycomb and trithorax are antagonistic repressors and activators 21.17 An LCR may control a domain 21.18 Insulators block enhancer actions 21.19 Insulators can vary in strength 21.20 A domain has several types of elements 21.21 Gene expression is associated with demethylation 21.22 CpG islands are regulatory targets