Disorders Associated with the Immune System Infection and immunosuppression are failures of the immune system. Superantigens cause release of cytokines that cause adverse host responses. Allergies and transplant rejection are harmful immune reactions Disorders Associated with the Immune System • Infection and immunosuppression are failures of the immune system. • Superantigens cause release of cytokines that cause adverse host responses. • Allergies and transplant rejection are harmful immune reactions