扬州大学毕报（农业与生命科学版 第24 mapping in natural etions Genetics,1.15789-909. 【9] er te lia Pat [52 he erosis in rice as reve ed by QTL analyais using em J].Ge 【3 JM.Rec 00.6:41-49 ton genes ative trait loci for g s in pigs[门.Science n and health of dair attle in a large out cer PM. 200 62,1863 Hanis C L,B [6o] Hll M A ,9,11,12,nd18 tion ir 172 1993,2 D L.et al. ptibility to diabetes 【641 n E J,C 156 (65]LiZ K.Pimse in rice (Oryea L.I].G ics,1997 [6 T FC.Qu 2000.155:1773-178s py and 1999,1531233-1243 Ea (C ine a OTL inte a t 16 [l.Nat Rev Ge look at gemetic archite in the u Rev Ecol Svst,199930:23-49. n E. US/ 2000,97 Gen tcs,1993,134,559-57 [) of maise:evid ce for epistasis and the of do .9 ic,195,11:333-346 【78 Spradling L79] EA er DD. ation of the s. e by gene deleric 1999 万方数据扬州大学学报(农业与生命科学版) 第24卷 ￡幅] [4 6] [4 7] [48] [641 【65 J [66] [6 7] [68] [69] wu R，ze“g z B Llnk89eandllnkage dls。qulm)r…mappj“gi…t…1 p。pulatlons[j]Genettcs，2001，157：899 909 cardoⅡL R-Bell JI Assoclatlon study designfo…】mplex dlse—s[J]NatRevG—t，2001．2：9l一99． HHstbacka J，Chapelle A，Kainla I，et al_Llnk39e dIs。qullibnuⅢm8pplog 1n isolated f。unde’populatlon3：dlastr。phlc dy8plasla ln F1nland LJ J．Nat…Genet，l 992，2：204—211． HHstbacka J，Chapelle A，Mahtanl M M．et a1 The diastrophic dysplasl8 g。neencodesaⅡovel sulfate transporter：positlonal clolli“g by fme struct—llnkage disequlllbrlummappl“g口]．cell，1 994，78：1073—1087． Paterson A H，Lander E S，H…tt J D，et a1 Res。lutlonof quantltatlve tralts into Mendelian factor by usl“g acomplete llnkage map of restnctlon ff89ment le“gth p。lymorphlsm口] Nat…，1 988，335：72l 726． Pater…AH，Damon S，H…¨JD，et a1 MeⅡdelianfact…nderlyl“g q…tltativetraltsint。mato：comparIso…r…specles， genrratlons，and…lronments[J]G…tics，1 991，1 27：181 197 Stuber(、W，Ll㈨ln S E．Wolff D W，et al_IdentlfIcat·on of g—tlc fact…con州butlng to heterosls in a hybrld from t…lne ma…nbred ll…usmg moIecul8…rkers[J]．Genetlcs，1992，132：823—839 Xlao J IIt I一1 J M，Yuan L P，et a1．Donun8nce ls th…Jo’genetlc basl80f hetefoslsln ri……vealed by QTL analys…sl“g Inol…】…arkers UJ G—tlcs，l 995，140：745 754． G10n J M，Rech P，G…a—Pettenatl J．et a1．M8pp1“g candidat8 g一…E…枷f…lth emphastson lignlficatlo“g—s[J] MoI Breedmg，2000，6：44l一449 An出rss。n L，Hal2y c s-Ell。gren H，et aI．Geneticmappl“g of q…tItatlve tran locl fo。g…th and fatnes蛐pigs[J]．scl…e， 1994，263 1 7 71 1774． Zh”g Q，Iklchard D，H。eschele I，et al_M8ppl“g(1uantItative locl formlIk productlonand health of daIry cattle in a 1a。ge out— bred pedlg。ee LJ』．Genetics，1998，149：1 959—1 973． McRae A F，McE…J c，D。dds K G，et a1_Llnk89。dls。qullibrlum ln do…tic sheep[J]．Geneticg，2002，160：111 3一11 22． Slate J．V1sscher P M，MacGr。gor S，et a1．A gen0㈣…fo‘q…tltatlve tralt locii…lld populatton of red deer(＆俐“毋 p^“j)[J]G…tlcs，2002，1 62：1 863一1873 F“nt J，Analys㈣f q…tltatlve tralt locl that lnfluen…nimal behavlor[J]．J N…oblol，2003，54i 46—7 7 Han】s c L，Bo…1nkle E，Chakroborty R，et al_A genomew甜ese8rch for humannon lnsulln—d。pendent(type 2)dlabete8 g—s r…al…8Jo㈣sceptlbll“y lo……hromosome 2[J]Nat G—t，1 996，1 3：1 61一166． Hall M A，N…an P Jt Thlel B，et a1．Q…titativc traIt loclon chromo啪es l，2，3，4，8，9 l…ls of T and Blymphocyt㈨bpopulations口]．Am JHumGenet，2002．70：1172—1182 Tanksky s D Mappl“g p01yg—s[J] Annu Rev Genet，1993。27：205 z33． Llndsley D L，z…G G．Th。genomeof D，．05。p^“d卅幽nog口s衙[M]．san Dl。g。：AcademIc，1992 Cox N J，Frlgge M，Ntcolae D L．et al_Locl on chr。mosome 2(Ⅳ，DDM，)and 15 Interact to i—ea…一。ptibllI‘y to dlabetes ln Mexl…A…1…s lJj NaI G㈣t．1 999．2l：2l 3 21 5． Rout…E J．Ch…fud j M．G…effectson a quantltatlve trait：t～10cusepIstatlceffect……r甜at microsatelllt㈨rkers and est…ted QTL【】]．Ev01utlon，1997，51：1 654 1662． “z K，Pl…n s R，Park w D，et a1．Epistasl8 for thre。g ral“yleld component8 lⅡrlce(0砷删f琊4 L¨)[J]．Genetlcs，1 997， 145：4 53 465． Le‘ps J，Mackay T F C．Quantltatlve traltloci for llfe 3p…n Dr哪叩^妇榭，…舭sf￡r：Interactlon wlth genetic backgTound and larva：dcnsl‘y[J J．G—tlcs，2000，155：1773 1788 shook 11 R．Joh…n T E Q…tnatlve tral“ocl affe“l“g…vlval and fer“ty—related tralts in G…0r^d耐“…f。舭…ho”g… ‘yp}…Ironme…nteractlons，plelotropy and eplstasls LJ J Genetlcs，1 999，1 53：1233一1243 P h1111ps P c．The 1a“gu89e of g—Interaction[J]．G—tlcs，1998，149：11 67一11 71 D…asl A Interval 8pecificco“genlcstrains(ISCS)：…1pe…ental deslgn fo…ppi。lg a QTL into a l一…tiMo‘g…nt…al lJ J Mamm Genome．1 997，8：1 63—1 67 Nadeau J Modlfle‘gen…㈣ceand h咖Ⅱs[J]Nat RevGenet，200l，2：165—174 Va“ghn T T，Pletscher S，Perlpato A，et a1．Mappllg quantitative trait locl formurlne growth ture[J]．Genet Res，l 999，74：31 3—322 Templeton A uses of evoluti。…y theo。y in the huma“genom。pro扣ct[J]A…Rev Ecol syst，1 999，30：23—49． cockerham c c，ze“g z B Deslgn_wlth marker loci口]．Genetics，1996，1437—1456 Frldman E，Pleban T，Z删r D．A recombination hotspot dellmltsawild一8pecie3 quantltatlve tralt Iocus for tomato sugarcontenl to 484 bp withln丑n i…rtas。gene[】]Proc Nad Acad Scl usA．2000，97：4718—4723． DoebI。y J，Stec A Inhent—e of them0。phological dlfferences betweenmatzeand teosinte：comparison of r…lts from two Fz populatlons LJ J，Genetlcs，1 993，134：559—570． Do曲l。y J，Stec A，Gustu3 C咖5Ⅲ押6，Ⅵnc^d 1 and the。figlnof州e：evldence for eplstasi…d th evolutlon of domiⅡance LJ J Genetlcs，1 995，141：333 346． Fra。y A，Nesbltt T c，Fra’y A，et a1．如2．2：8 qllantltative trait l…s k。y to th…olutlon of tomato frulf slze[J]sci…e， 2000，289：85—88 Spradll“g A C，St…Dt Bealon A，et al_The Herkeley Dr。s砷^f缸genom。gene dlsruptio“pro】ect：sl“gle P element lnsertlons mut8tmg 25％of vltal Dr∞印^l妇genes[j]．Genetlcs，1999，153：135～l 77 Wmzeler EA，Shoemaker D D，AstromoffA，et a1．Functlonal characteri粕tion ofthe S．㈣缸c g蛐啪e by g。ne deleti…nd parallel analysls口]．Science，1999，285l 901—906 m 呈_ ㈣ m m m m _!兰_m _翌=呻 呈l m m旧 加¨ 他"n ％ ％ " 碍 伯 万方数据