1.亲核加成 Nucleophilic addition HCN C=C-C=O 1R2 CuLi 2)H2O D)RMgX, CuCI 2)H3O D)RLI 2)H2O DRMgX 2 2)H2O (1,4-1. 亲核加成 Nucleophilic addition C=C-C=O HCN 1,4- NH 1,4- 1) R2CuLi 2)H2O 1,4- 1) RMgX,CuCl 2)H3O + 1,4- 1) RLi 2) H2O 1,2- 1) RMgX 2)H2O (1,2- ) (1,2- ) (1,4- )