2/16/2016 Survival and Growth in Foods Characteristics of Disease Sensitive to Shigellosis is differentiated from other ·3.8-5.2%NaC1atpH4.8-5.0 diseases caused by foodborne pathogens ·300-700 mg of NaN02 1.Production of bloody diarrhea 0.5-1.5 mg of sodium hypochlorite 2.Low infectious dose dissolved in water at 40C (bleach) ·ionizing radiation Characteristics of Disease Characteristics of Disease Dysentery involves bloody diarrhea Shigella is easily transmitted 1.Bloody mucoid stools-40% 1.passed from person to person by food 2.Severe abdominal pain-100% 3.Rectal pain -100% 2.by poor hygiene 4.Cramps 3.multiplies rapidly at room temperature 5.Fever-33% 4.produces a powerful Shiga toxin once in During dysentery stage,extensive bacterial the host colonization of the colon and invasion of colon cells occur 5.causes an infection not an intoxication Dead cells slough off leading to blood,pus,and 6.low dose,100 cells ingested mucus in the stools 62/16/2016 6 Survival and Growth in Foods Sensitive to • 3.8-5.2% NaCl at pH 4.8-5.0 • 300-700 mg of NaNO2 • 0.5-1.5 mg of sodium hypochlorite dissolved in water at 4OC (bleach) • ionizing radiation Characteristics of Disease • Shigellosis is differentiated from other di d b f db diseases caused by foodborne pathogens 1. Production of bloody diarrhea 2. Low infectious dose Characteristics of Disease Dysentery involves bloody diarrhea 1. Bloody mucoid stools – 40% 2. Severe abdominal pain – 100% 3. Rectal pain – 100% 4. Cramps 5. Fever – 33% During dysentery stage extensive bacterial During dysentery stage, extensive bacterial colonization of the colon and invasion of colon cells occur Dead cells slough off leading to blood, pus, and mucus in the stools Characteristics of Disease Shigella is easily transmitted 1. passed from person to person by food 2. by poor hygiene 3. multiplies rapidly at room temperature 4. produces a powerful Shiga toxin once in the host 5. causes an infection not an intoxication 6. low dose, <100 cells ingested