1.羰基与含碳亲核试剂的加成 (1The Addition of Gringard Reagents (1)Et2O CH3h2CH-C-CH(CH3)2 CH3 CH,MgBr (2)H3O OH X(CH3)2CH-C-CH(CH3)2 80 CH2CH 空间位阻增大时,加成的产率降低Organic Chemistry Organic Chemistry Xiamen Xiamen University University 1. 羰基与含碳亲核试剂的加成 (1)The Addition of Gringard Reagents (C H 3 ) 2CH C CH(CH 3 ) 2 O + CH 3CH 2MgBr (1) E t 2 O (2) H 3 O + (C H 3 ) 2CH C CH(CH 3 ) 2 OH CH 2CH 3 80% 空间位阻增大时 加成的产率降低