Type ll hypersensitivity A Complement- and Fc receptor-mediated inflammation Complemen Ags on the surface of target cells body >IgG, IgM (B Opsonization and phagocytosis 1. damage the target cell 1 activation of complement Phagocyte 2)opsonization FcR C3bR mplement 3)ADCC activator 2. target cell dysfunction Antibody against Antibody stimulat ntibody inhibits binding receptor without hor of neurotransmitter to receptor ElsevierAbbas&LichtmanBasicImmunology,updated2e-www.studentconsult.comType II hypersensitivity Ags on the surface of target cells ↓ body→IgG, IgM ↓ 1. damage the target cell 1) activation of complement 2) opsonization FcR C3bR 3) ADCC 2. target cell dysfunction