ORGANIC CHEMISTRY Chapter 16 Mechanisms 1. Addition of a Strong Nucleophile to an Aldehyde or Ketone R/88 R C=0 R C-O、H<M,R R LRIC-OH Nu NI NI The important aspect of this step is the ability of the carbonyl oxygen atom to accommodate the electron pair of the carbon-oXygen double bond Department of Chemistry, Xiamen UniversityORGANIC CHEMISTRY Department of Chemistry, Xiamen University Chapter 16 Mechanisms Mechanisms 1. Addition of a Strong Nucleophile to an Aldehyde or Ketone C O R' R δ− δ+ Nu C O R' R Nu H Nu C OH R' R Nu The important aspect of this step is the ability of the carbonyl oxygen atom to accommodate the electron pair of the carbon-oxygen double bond