E chemical reagents react with the backbone phosphates 7. Thymidine a is equal to the adenosine concentration in double-stranded DNA b is replaced by Uracil in RNA c normally forms 2 hydrogen bonds with adenosine D can participate in hydrophobic interactions due to its methyl group E All of the above are correct 8. The major and minor grooves of B-form DNA correspond to what features of A-form rNA? a minor and major grooves b deep and shallow grooves D phosphoribose backbones E Choices a) and d)are both correct 9. The glycosid ic bonds in DNA and rna A be hydrolyzed by o b are free to rotate over about 180 c are restricted to one of four possible orientations E stabilize Watson-Crick H-bonds 10. In solution, the grooves of nucleic acid helices a are filled with H2O and counterions(M*& m2t) B expose the H-bonding groups of the bases c expose the hydrophobic surfaces of the bases D are about equal in width E Choices a) and b)are both correct 11. When an aromatic molecule intercalates into the dna double helix the two adjacent base pairs are separated by about and the helix is unwound by about A342,36° B4.3?,36° C3.4?.26° D4.3?,26 E1.7?,10° 12. If your genomic DNA could be typed for a specific genetic defect a "I would not want to be tested ever b "I would want to be tested now C I might want to be tested laterE chemical reagents react with the backbone phosphates. 7. Thymidine A is equal to the adenosine concentration in double-stranded DNA. B is replaced by Uracil in RNA. C normally forms 2 hydrogen bonds with adenosine. D can participate in hydrophobic interactions due to its methyl group. E All of the above are correct. 8. The major and minor grooves of B-form DNA correspond to what features of A-form RNA? A minor and major grooves B deep and shallow grooves C deoxyribose backbones D phosphoribose backbones E Choices a) and d) are both correct. 9. The glycosidic bonds in DNA and RNA A can be hydrolyzed by OH- . B are free to rotate over about 180°. C are restricted to one of four possible orientations. D connect the sugar to the base. E stabilize Watson-Crick H-bonds. 10. In solution, the grooves of nucleic acid helices A are filled with H2O and counterions (M+ & M2+). B expose the H-bonding groups of the bases. C expose the hydrophobic surfaces of the bases. D are about equal in width. E Choices a) and b) are both correct. 11. When an aromatic molecule intercalates into the DNA double helix, the two adjacent base pairs are separated by about ______, and the helix is unwound by about _______. A 3.4?, 36° B 4.3?, 36° C 3.4?, 26° D 4.3?, 26° E 1.7?, 10° 12. If your genomic DNA could be typed for a specific genetic defect A "I would not want to be tested, ever." B "I would want to be tested now." C "I might want to be tested later