Physiologic Atrophy o A good example is that of endometrium and breast which occurs with menopause and the loss of estrogen stimulation. o Uterine involution Thymic atrophy after puberty In the aging process,atrophy may be a normal morphologic changes,e.g.the brain and heart.Physiologic Atrophy A good example is that of endometrium and breast which occurs with menopause and the loss of estrogen stimulation. Uterine involution Thymic atrophy after puberty In the aging process, atrophy may be a normal morphologic changes, e.g. the brain and heart