Adults Symptoms Easy fatigability Coldness Weight gain t Constipation Menstrual irregularities Signs ◆C0ol, rough, dry skin ◆ Puffy face and hands Hoarse and husky voice Slow reflexes t Yellowish color skinAdults Symptoms  Easy fatigability  Coldness  Weight gain  Constipation  Menstrual irregularities Signs  Cool, rough, dry skin  Puffy face and hands  Hoarse and husky voice  Slow reflexes  Yellowish color skin