BIOMATERIALS-TISSUE INTERACTIONS Permanent biomaterials ° Positive response Tissue attachment ° Adverse responses Contraction Reaction to particles; tissue destruction ° Passive responseBIOMATERIALS BIOMATERIALS -TISSUE INTERACTIONS INTERACTIONS Permanent Biomaterials Permanent Biomaterials • Positive Response Positive Response –Tissue attachment Tissue attachment • Adverse Responses Adverse Responses –Contraction Contraction –Reaction to particles; Reaction to particles; tissue destruction tissue destruction • Passive Response Passive Response