Silicon-Tethered reactions B A-B Duke m. fitch Evans Group Seminar March 15. 1996 Bols, M; Skrydstrup, T. Chem. Rev. 1995, 95, 1253-1277 Cycloadditions A. 5-Atom Tether Ring 2.区2 3.[5+2] B. 6-Atom Tether Ring C 7-Atom Tether Ring 1. Type I and ll Diels-Alder D. 8-Atom and Larger Tether Rings 1. Type Il Diels-Alder Radical reactions A. 5-EXo-and 6-Endo- Ring Formations 1. Trig-Cyclizations 2. Dig-Cyclizations B. 6-EXo-and 7-Endo-Ring Formations lIL Silicon Addition to double bonds A. Addition to c=c Bonds 1. Hydrosilylation Bis-silylation B. Addition to c=o bonds Ⅳ. Nucleophile Delivery 33A-013/149611:15PMA + B A + B A B Si A Silicon-Tethered Reactions B Si Duke M. Fitch Evans' Group Seminar March 15, 1996 Review: Bols, M.; Skrydstrup, T. Chem. Rev. 1995, 95, 1253-1277. I. Cycloadditions A. 5-Atom Tether Ring 1. [4 + 2] 2. [2 + 2] 3. [5 + 2] B. 6-Atom Tether Ring C. 7-Atom Tether Ring 1. Type I and II Diels-Alder D. 8-Atom and Larger Tether Rings 1. Type II Diels-Alder II. Radical Reactions A. 5-Exo- and 6-Endo- Ring Formations 1. Trig-Cyclizations 2. Dig-Cyclizations B. 6-Exo- and 7-Endo- Ring Formations C. Others III. Silicon Addition to Double Bonds A. Addition to C=C Bonds 1. Hydrosilylation 2. Bis-silylation B. Addition to C=O Bonds IV. Nucleophile Delivery 33A-01 3/14/96 11:15 PM