Epidermis CNS Ventral BMP Chordin Dorsal Noggin Mesoderm Spemann's Organizer At gastrula a gradient of BMP4 is established by a ventral source of BMP4 and a dorsal source of chordin and noggin, two bMP antagonists secreted by the dorsal organizing centerDorsal Ventral Spemann’s Organizer Epidermis CNS At gastrula a gradient of BMP4 is established by a ventral source of BMP4 and a dorsal source of Chordin and Noggin, two BMP antagonists secreted by the dorsal organizing center. Mesoderm Endoderm Fig. 7b