Pathogenesis Trophozoites Attach to mucosal epithelial cells (MEC) Lyse mec Ulcerate and invade mucosa Cause dysentery(diarrhea + blood) Metastasize via blood &/or lymph to Form abscesses in extraintestinal sitesTrophozoites ... – Attach to mucosal epithelial cells (MEC) – Lyse MEC – Ulcerate and invade mucosa – Cause dysentery (diarrhea + blood) – Metastasize via blood &/or lymph to – Form abscesses in extraintestinal sites ... Pathogenesis