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1222 工程科学学报,第43卷.第9期 (3)今后的研究可通过改进可穿戴式传感器 [10]Pfeifer M A,Cook D,Brodsky J,et al.Quantitative evaluation of 的设计,采集多种人体生理数据(如PPG、脑电信 cardiac parasympathetic activity in normal and diabetic man 号及血氧含量等),实现多模生理信号的融合,这 Diabetes,1982,31(4pt1):339 对于今后无创血糖技术的发展及可穿戴的个性化 [11]Porumb M,Stranges S,Pescape A,et al.Precision medicine and 健康监测设备的研制有重大的意义 artificial intelligence:A pilot study on deep learning for hypoglycemic events detection based on ECG.Sci Rep,2020,10: 参考文献 170 [12]Jin X F,Liu C H.Xu T L,et al.Artificial intelligence biosen- [1]Wan X S.Review of the risk factors and intervention of type 2 diabetes.Chin J Soc Med,2006,23(4):251 sors:Challenges and prospects.Biosens Bioelectron,2020,165: 112412 (万晓珊.2型糖尿病的危险因素及干预综述.中国社会医学杂 志,2006,23(4):251) [13]Tobore I,Kandwal A,Li JZ,et al.Towards adequate prediction of [2] Zheng C Z,Ding D.Guiding opinions of Chinese diabetes surgery prediabetes using spatiotemporal ECG and EEG feature analysis experts (2010).Chin J Pract Surg,2011,31(1):54 and weight-based multi-model approach.Know/Based Syst,2020, 209:106464 (郑成竹,丁丹.中国糖尿病外科治疗专家指导意见(2010).中国 实用外科杂志,2011.31(1):54) [14]Kandhasamy J P,Balamurali S.Performance analysis of classifier [3]Hou Q T.Li Y.Li S Y,et al.The global burden of diabetes models to predict diabetes mellitus.Procedia Comput Sci,2015, mellitus.Chin./Diabetes,2016,24(1):92 47:45 (侯清涛,李芸,李舍予,等.全球糖尿病疾病负担现状.中国糖 [15]Tafa Z,Pervetica N,Karahoda B.An intelligent system for 尿病杂志,2016,24(1):92) diabetes prediction//2015 4th Mediterranean Conference on [4] Zheng Z J.Application of Continuous Glucose Monitoring System Embedded Computing (MECO).Budva,2015:378 in Critical Illness:A Preliminary Study [Dissertation].Hangzhou: [16]Liu Y W.Research on Non-Imasive Blood Glucose Detection Zhejiang University,2016 Based on PPG and ECG Fusion Signal [Dissertation].Guangzhou: (郑忠骏.连续血糖监测系统在危重患者中应用的初步研究学 Guangdong University of Technology,2018 位论文].杭州:浙江大学,2016) (刘宇巍.基于PPG和ECG信号融合的无创血糖检测方法研究 [5]Wei Z,Zhang B X,Shi H B,et al.The development of [学位论文].广州:广东工业大学,2018) noninvasive detection technique of blood glucose.China Med [17]Feng P H.Research on Blood Glucose Estimation Based on Signal Equp,2020,17(12):196 Processing Technology [Dissertation].Guangzhou:Guangdong (韦哲,张秉玺,石恒兵,等.无创血糖检测技术的发展.中国医 University of Technology,2019 学装备,2020,17(12):196) (冯培华,基于信号处理技术的无创血糖估计研究[学位论文] [6]Wang L P.Study on Approach of ECG Classification with Domain 广州:广东工业大学,2019) Knowledge [Dissertation].Shanghai:East China Normal [18]Tobore I,Li J,Yuhang L,et al.Deep learning intervention for University,2013 health care challenges:Some biomedical domain considerations. (王丽苹,融合领域知识的心电图分类方法研究学位论文].上 JMIR Mhealth Uhealth,2019,7(8):e11966 海:华东师范大学,2013) [19]Tobore I,Li J,Kandwal A,et al.Statistical and spectral analysis of [Liu C Y,Yang M C.Di J N,et al.Wearable ECG:History,key ECG signal towards achieving non-invasive blood glucose technologies and future challenges.ChinJ Biomed Eng.2019, monitoring.BMC Med Inform Decis Mak,2019,19(Suppl6):266 38(6):641 [20]Chen W,Xie X S,Wang JL,et al.A comparative study of logistic (刘澄玉,杨美程,邸佳楠,等.穿戴式心电:发展历程、核心技术 model tree,random forest,and classification and regression tree 与未来挑战.中国生物医学工程学报,2019,38(6):641) models for spatial prediction of landslide susceptibility.CATENA, [8]Wang J H.What are the hazards of hyperglycemia and 2017,151:147 hypoglycemia.Prevent treat cardiovasc,2016(4):19 [21]Yang H B,Wu X W,Yuan R,et al.Establishment and verification (王建华.高血糖、低血糖各有哪些危害.心血管病防治知识, of the prediction model and nomogram for type 2 diabetes blood 2016(4):19) glucose control [J/OL].J Chengdu Med College (2020-7-22) [9]Acharya U R,Fujita H,Lih O S,et al.Automated detection of [2020-12-30].htp:/Mns.cnki.net/kcms/detail/51.1705.R.20200722 coronary artery disease using different durations of ECG segments 1640.004.html with convolutional neural network.Know/Based Syst,2017,132: (杨恒博,吴行伟,袁蓉,等.2型糖尿病血糖控制预测模型及列 62 线图的建立与验证卫/0L.成都医学院学报(2020-7-22)[2020-(3)今后的研究可通过改进可穿戴式传感器 的设计,采集多种人体生理数据(如 PPG、脑电信 号及血氧含量等),实现多模生理信号的融合,这 对于今后无创血糖技术的发展及可穿戴的个性化 健康监测设备的研制有重大的意义. 参    考    文    献 Wan  X  S.  Review  of  the  risk  factors  and  intervention  of  type  2 diabetes. Chin J Soc Med, 2006, 23(4): 251 (万晓珊. 2型糖尿病的危险因素及干预综述. 中国社会医学杂 志, 2006, 23(4):251) [1] Zheng C Z, Ding D. Guiding opinions of Chinese diabetes surgery experts (2010). Chin J Pract Surg, 2011, 31(1): 54 (郑成竹, 丁丹. 中国糖尿病外科治疗专家指导意见(2010). 中国 实用外科杂志, 2011, 31(1):54) [2] Hou  Q  T,  Li  Y,  Li  S  Y,  et  al.  The  global  burden  of  diabetes mellitus. Chin J Diabetes, 2016, 24(1): 92 (侯清涛, 李芸, 李舍予, 等. 全球糖尿病疾病负担现状. 中国糖 尿病杂志, 2016, 24(1):92) [3] Zheng Z J. Application of Continuous Glucose Monitoring System in Critical Illness: A Preliminary Study [Dissertation]. Hangzhou: Zhejiang University, 2016 ( 郑忠骏. 连续血糖监测系统在危重患者中应用的初步研究[学 位论文]. 杭州: 浙江大学, 2016) [4] Wei  Z,  Zhang  B  X,  Shi  H  B,  et  al.  The  development  of noninvasive  detection  technique  of  blood  glucose. China Med Equip, 2020, 17(12): 196 (韦哲, 张秉玺, 石恒兵, 等. 无创血糖检测技术的发展. 中国医 学装备, 2020, 17(12):196) [5] Wang L P. Study on Approach of ECG Classification with Domain Knowledge [Dissertation].  Shanghai:  East  China  Normal University, 2013 ( 王丽苹. 融合领域知识的心电图分类方法研究[学位论文]. 上 海: 华东师范大学, 2013) [6] Liu C Y, Yang M C, Di J N, et al. Wearable ECG: History, key technologies  and  future  challenges. Chin J Biomed Eng,  2019, 38(6): 641 (刘澄玉, 杨美程, 邸佳楠, 等. 穿戴式心电: 发展历程、核心技术 与未来挑战. 中国生物医学工程学报, 2019, 38(6):641) [7] Wang  J  H.  What  are  the  hazards  of  hyperglycemia  and hypoglycemia. Prevent treat cardiovasc, 2016(4): 19 (王建华. 高血糖、低血糖各有哪些危害. 心血管病防治知识, 2016(4):19) [8] Acharya  U  R,  Fujita  H,  Lih  O  S,  et  al.  Automated  detection  of coronary artery disease using different durations of ECG segments with convolutional neural network. Knowl Based Syst, 2017, 132: 62 [9] Pfeifer M A, Cook D, Brodsky J, et al. Quantitative evaluation of cardiac  parasympathetic  activity  in  normal  and  diabetic  man. Diabetes, 1982, 31(4pt1): 339 [10] Porumb M, Stranges S, Pescapè A, et al. Precision medicine and artificial  intelligence:  A  pilot  study  on  deep  learning  for hypoglycemic events detection based on ECG. Sci Rep, 2020, 10: 170 [11] Jin  X  F,  Liu  C  H,  Xu  T  L,  et  al.  Artificial  intelligence  biosen￾sors:  Challenges  and  prospects. Biosens Bioelectron,  2020,  165: 112412 [12] Tobore I, Kandwal A, Li J Z, et al. Towards adequate prediction of prediabetes  using  spatiotemporal  ECG  and  EEG  feature  analysis and weight-based multi-model approach. Knowl Based Syst, 2020, 209: 106464 [13] Kandhasamy J P, Balamurali S. Performance analysis of classifier models  to  predict  diabetes  mellitus. Procedia Comput Sci,  2015, 47: 45 [14] Tafa  Z,  Pervetica  N,  Karahoda  B.  An  intelligent  system  for diabetes  prediction//2015  4th Mediterranean Conference on Embedded Computing (MECO). Budva, 2015: 378 [15] Liu  Y  W. Research on Non-Invasive Blood Glucose Detection Based on PPG and ECG Fusion Signal [Dissertation]. Guangzhou: Guangdong University of Technology, 2018 ( 刘宇巍. 基于PPG和ECG信号融合的无创血糖检测方法研究 [学位论文]. 广州: 广东工业大学, 2018) [16] Feng P H. Research on Blood Glucose Estimation Based on Signal Processing Technology [Dissertation].  Guangzhou:  Guangdong University of Technology, 2019 ( 冯培华. 基于信号处理技术的无创血糖估计研究[学位论文]. 广州: 广东工业大学, 2019) [17] Tobore  I,  Li  J,  Yuhang  L,  et  al.  Deep  learning  intervention  for health  care  challenges:  Some  biomedical  domain  considerations. JMIR Mhealth Uhealth, 2019, 7(8): e11966 [18] Tobore I, Li J, Kandwal A, et al. Statistical and spectral analysis of ECG  signal  towards  achieving  non-invasive  blood  glucose monitoring. BMC Med Inform Decis Mak, 2019, 19(Suppl6): 266 [19] Chen W, Xie X S, Wang J L, et al. A comparative study of logistic model  tree,  random  forest,  and  classification  and  regression  tree models for spatial prediction of landslide susceptibility. CATENA, 2017, 151: 147 [20] Yang H B, Wu X W, Yuan R, et al. Establishment and verification of the prediction model and nomogram for type 2 diabetes blood glucose  control  [J/OL]. J Chengdu Med College (2020-7-22) [2020-12-30]. http://kns.cnki.net/kcms/detail/51.1705.R.20200722. 1640.004.html ( 杨恒博, 吴行伟, 袁蓉, 等. 2型糖尿病血糖控制预测模型及列 线图的建立与验证[J/OL]. 成都医学院学报(2020-7-22) [2020- [21] · 1222 · 工程科学学报,第 43 卷,第 9 期
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