药物化学期末考试(B)卷答案 1.完成下列反应(20分，每空2分) H.C-NCI CsH5CH2CN H2S04 NaNH2△ H;C-N H20 H3C-N COOCH(CH3h 1-methyl-4-phenyl-4-piperidine-carboxylic acid isopropyl ester NH2OH.HCI NOH CICH2COCI NaOH 扩环 7-chloro-5-pheny-1,3-dihydro-2H-1,4-benzodiazepin- 2-one-4-oxide.药物化学期末考试（B）卷答案 1. 完成下列反应（20 分,每空 2 分） H3C N Cl Cl C6H5CH2CN NaNH2 H2SO4 H2O 1-methyl-4-phenyl-4-piperidine- carboxylic acid isopropyl ester H3C N CN H3C N COOH (CH3)2CHOH H3C N COOCH(CH3 )2 O N Cl Fe. HCl NH2 Cl NOH ClCH2COCl 7-chloro-5-pheny-1,3-dihydro-2H-1,4-benzodiazepin- 2-one-4-oxide. NaOH NH2OH. HCl NH2 Cl O N H N O Cl O