Outline Brief review of protein structure Chou-Fasman predictions Garnier, Osguthorpe and robson Helical wheels and hydrophobic moments Neural networks Nearest neig hbor methods Consensus prediction approachesOutline • Brief review of protein structure • Chou-Fasman predictions • Garnier, Osguthorpe and Robson • Helical wheels and hydrophobic moments • Neural networks • Nearest neighbor methods • Consensus prediction approaches