2. What Causes Cancer Chemical Exposure Behavior(Tobacco smoke -> lung cancer) Environmental (polychlorinated biphenyl,(PCBs) Occupational (coal tar, asbestos aniline dye) Diet (aflatoxin-> liver cancer Radiation(UV-> Xeroderma pigmentosum, ionizing Infection Viruses(Epstein-Barr virus(EBv)-> lymphoma, hepatitis B->liver cancer, papilloma-> cervical cancer etc) Inherited familial cancer syndromes Mutations and or chromosomal abnormalities Most, if not all, of these causes have their genetic underpinning linked with cancer.2. What Causes Cancer? • Chemical Exposure – Behavior (Tobacco smoke -> lung cancer) – Environmental (polychlorinated biphenyl, (PCBs)) – Occupational (coal tar, asbestos, aniline dye) – Diet (aflatoxin -> liver cancer) • Radiation (UV -> xeroderma pigmentosum,ionizing) • Infection – Viruses (Epstein–Barr virus (EBV) -> lymphoma, hepatitis B -> liver cancer, papilloma -> cervical cancer etc) • Inherited familial cancer syndromes • Mutations and/or chromosomal abnormalities Most, if not all, of these causes have their genetic underpinning linked with cancer